D-mannose for Cats Dosage

D-mannose for Cats Dosage

Have you, as a veterinarian, ever advised a client to use D-Mannose to prevent UTI? What do you usually advise to prevent UTI, which are one of the main reasons for vet visits?

1
I’m not a vet, but a doctor. I do advise D-Mannose to patients. It’s very good for prevention of UTIs and also to help get over the infection faster. I recommend mixing with water and drinking a lot afterwards. Allow 30 mins-to an hour before going to the restroom so it has time to coat the bladder. If there is any inappropriate hygiene going on that could explain them or if they are not drinking enough water.
2
Urinary tract infections are not one of the main reason for vet visits in our area. Allergies and flea infestations are way more common here. We see few urinary tract infections in dogs unless they are secondary to another underlying problem, such as bladder stones, diabetes, vulvar or preputial infections. Cats can suffer from urinary tract infections but more commonly suffer from urinary ‘sand’ causing irritation and blockage as the urinary crystals get too big to pass. Infections here in cats are often secondary to something else as well. So I don’t prescribe anything to PREVENT UTI except drinking a lot of water, feeding cats canned food, reducing feline stress, and appropriately treating vulvar/vaginal/preputial/prostate infections. I don’t believe in feeding cats the ‘urinary tract health’ diets found over the counter in stores because the reasons for urinary tract problems in cats are multifactorial, so one food cannot prevent all the ways a urinary tract can go south. Plus, those foods are mostly dry, which is not the type of food to feed a cat to prevent urinary tract problems!
3
Not a vet but a registered veterinary technician for 23 years. I’ve never heard of a vet prescribing that. UTIs aren’t all that common in pets. Crystalluria is common in cats but that’s not usually associated with infection. The two main reasons people bring their pets in are skin problems and gastrointestinal issues.
4
I have not, in fact, ever prescribed D-mannose. There is a lot of confusion about what causes urinary tract symptoms in cats. The confusion is likely due to the issue that there are three major types of lower urinary tract disease and they all have the same basic signs.

I wrote a blog post a while back about just this problem:

The most common problem seen causing frequent urination, blood in the urine and urination outside of the litter box is dehydration that leads to overly concentrated urine and crystal formation in the bladder. The crystals can cause stones to form, scratches in the bladder and urethra (thus the blood), and urethral blockage. Treatment for these cats is diet change to canned only diets that increase water consumption and decrease the concentration of the urine in the bladder as well as provide the right balance of ingredients to maintain a normal pH of 6.5. It is best for all cats to have a primarily canned diet to maintain hydration and a healthy urinary tract.

There is also a large subset of cats that get lower urinary tract problems associated with stress. This problem is called idiopathic cystitis. Dr Tony Buffington at the Ohio State University has done a great deal of research in this area and has a website that goes into the problem in depth as part of the indoor pet initiative.

Indoor Pet Initiative

Basically what happens in these cases is that the bladder lining becomes leaky when a cat gets stressed, leading to blood in the urine and the same symptoms as those in the first group.

Treatment for idiopathic cystitis is maintaining the lowest possible level of stress for a cat and increasing water consumption to make urine as non-irritating to the bladder as possible. In the past it was thought that compounds that are similar to the lining of the bladder given orally could help to maintain bladder health, but all studies in this area failed to show any improvement in cats given the medications over the ones given placebos.

Only a very small number of cats with urinary tract signs can be shown to have infection. Those cats will be seen to have bacteria or large numbers of white blood cells in their urine when a urinalysis is done at your veterinarian’s office.

Those few that have infection (UTI) need to be given antibiotics for 10 to 20 days, depending on how severe the infection is and how long it has been going on.

The most important thing to know about urinary symptoms in cats is that a veterinarian needs to look at the cat’s urine in order to determine which treatment is needed for the individual cat.

For prevention, I recommend feeding a high quality canned diet that is mostly, if not all, animal protein. High animal protein diets produce the correct pH urine and the canned diet provides adequate water in the diet to produce normally dilute urine.

It is also important to provide environmental enrichment and low stress for our cats, who are, in most cases, indoor only cats and this are actually much like zoo animals. We need to provide all of the enrichment to make up for our cat’s not having trees to climb or small animals to chase. Most indoor cats are very bored and this leads to stress and stress related diseases like lower urinary tract inflammatory disease.
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